High-volume Versus Standard Volume Plasma Exchange in Patients With Acute Liver Failure With Cerebral Edema

NANot yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

December 1, 2025

Primary Completion Date

March 1, 2026

Study Completion Date

March 1, 2026

Conditions
Acute Liver FailureCerebral Edema
Interventions
PROCEDURE

High Volume Therapeutic Plasma Exchange

Experimental- High Volume Therapeutic Plasma Exchange at (8 - 9 litres of plasma would be exchanged in each patient over 6 - 8 hours)

PROCEDURE

Standard volume therapeutic plasma exchange

Active Comparator - The standard volume strategy would be performed centrifugation technique with Plasma volume varying from 1.5 - 2.5 times the plasma - volume along with Standard Medical Treatment.

Trial Locations (1)

110070

Institute of Liver & Biliary Sciences, New Delhi

All Listed Sponsors
lead

Institute of Liver and Biliary Sciences, India

OTHER

NCT06515145 - High-volume Versus Standard Volume Plasma Exchange in Patients With Acute Liver Failure With Cerebral Edema | Biotech Hunter | Biotech Hunter