Comparison of Remimazolam and Propofol on Emergence in Elderly Orthopedic Patients Under General Anesthesia

PHASE4CompletedINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

February 1, 2023

Primary Completion Date

September 30, 2023

Study Completion Date

October 31, 2023

Conditions
Hip Fracture
Interventions
DRUG

Remimazolam

In Remimazolam group, the induction dose of remimazolam is 0.3 mg/kg based on previous studies, the maintenance of anesthesia is 0.3-0.7 mg/kg/hr.

DRUG

Flumazenil

Immediately after the cessation of remimazolam infusion in PACU(PACU, Postanesthesia care unit), the nurses who are blind to the anesthesia management were asked to administer the flumazenil.

DRUG

Propofol

For propofol group, the induction of propofol is 1.5-2.0 mg/kg, followed by the maintenance of propofol infusion with 6-8 mg/kg/hr throughout the surgical procedure.

Trial Locations (2)

410011

Department of Anesthesiology, The Second Xiangya Hospital, Changsha

The Second Xiangya Hospital, Changsha

All Listed Sponsors
lead

Central South University

OTHER