30
Participants
Start Date
July 30, 2024
Primary Completion Date
July 30, 2026
Study Completion Date
December 31, 2026
Donafenib
200 mg BID,oral administration will start before the first HAIC treatment .
Sintilimab
200 mg Q3W,Intravenous infusion will perform before HAIC treatment.
HAIC
HAIC,Q3W. The total number of HAIC treatments was determined by the investigator based on patient needs. Dose: Oxaliplatin 85 mg / m2 for 2h, Calcium folinate 400 mg / m2 for 2h, 5-FU 400 mg / m2 for 10min, followed by 5-FU 1200 mg / m2 for 23 hours).
Tianjin Medical University Cancer Institute and Hospital
OTHER