A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA)

PHASE3RecruitingINTERVENTIONAL
Enrollment

630

Participants

Timeline

Start Date

July 30, 2024

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2027

Conditions
Geographic Atrophy
Interventions
DRUG

ANX007

Form: solution for injection; Route of Administration: IVT injection

OTHER

Sham Administration

Form and Route of Administration: to mimic IVT injection (includes placement of the blunt opening of an empty, needleless syringe barrel on the conjunctiva in the inferotemporal quadrant of the eyeball to stimulate the pressure of an injection).

Trial Locations (117)

1085

RECRUITING

Semmelweis Egyetem, Budapest

1133

RECRUITING

Budapest Retina Associates, Budapest

2000

RECRUITING

Sydney Eye Hospital, Sydney

RECRUITING

Sydney Retina Clinic and Day Surgery, Sydney

2135

RECRUITING

Strathfield Retina Clinic, Melbourne

2150

RECRUITING

Marsden Eye Specialists, Parramatta

2640

RECRUITING

Eye Clinic Albury Wodonga, Albury

4020

RECRUITING

Kepler Universitätsklinikum, Linz

6011

RECRUITING

Capital Eye Specialists, Te Aro

7681

RECRUITING

Ganglion Medical Center, Pécs

8013

RECRUITING

Southern Eye Specialists, Christchurch

10022

COMPLETED

Vitreous Retina Macula Consultants of NY (VRMNY), New York

11788

RECRUITING

Long Island Vitreoretinal Consultants, Hauppauge

14012

RECRUITING

Hospital de la Arruzafa - Metavisión Arruzafa, Córdoba

16507

RECRUITING

Erie Retina Research, LLC, Erie

17036

RECRUITING

Dietrich Bonhoeffer Klinikum Klinik für Augenheilkunde, Neubrandenburg

18704

RECRUITING

Eye Care Specialists, Kingston

20132

RECRUITING

IRCCS Ospedale San Raffaele, Milan

20815

RECRUITING

Retina Group of Washington, Chevy Chase

21079

RECRUITING

CHU Dijon Bourgogne - Hôpital François Mitterrand, Dijon

21740

RECRUITING

Cumberland Valley Retina Consultants, Hagerstown

RECRUITING

Mid Atlantic Retina Specialists, Hagerstown

24502

RECRUITING

Piedmont Eye Center, Lynchburg

27103

RECRUITING

Piedmont Retina Specialists - Winston Salem Office, Winston-Salem

27587

RECRUITING

North Carolina Retina Associates, Wake Forest

28222

RECRUITING

Hospital Universitario Puerta de Hierro - Majadahonda, Majadahonda

28803

RECRUITING

Asheville Eye Associates - Retina Division, Asheville

29414

RECRUITING

Charleston Neuroscience Center, Charleston

29801

RECRUITING

Palmetto Retina Center, Aiken

29901

RECRUITING

ReƟna Consultants of Charleston, Beaufort

30060

RECRUITING

Georgia Retina PC, Marietta

32216

COMPLETED

Florida Retina Institute- Jacksonville, Jacksonville

32308

RECRUITING

Southern Vitreoretinal Associates, Tallahassee

32806

RECRUITING

Florida Retina Institute, Orlando

33064

RECRUITING

Rand Eye Institute, Deerfield Beach

33324

RECRUITING

Fort Lauderdale Eye Institute, Plantation

33711

RECRUITING

Retina Vitreous Associates of Florida, St. Petersburg

33912

RECRUITING

National Ophthalmic Research Institute, Fort Myers

34233

RECRUITING

Retina Group of Florida, Sarasota

34994

RECRUITING

East Florida Eye Institute, Stuart

37203

RECRUITING

Tennessee Retina PC, Nashville

40509

NOT_YET_RECRUITING

Retina Associates of Kentucky, Lexington

41009

RECRUITING

Hospital Universitario Virgen Macarena, Seville

44106

RECRUITING

University Hospitals Cleveland Medical Center, Cleveland

44195

NOT_YET_RECRUITING

Cleveland Clinic Foundation, Cleveland

46100

RECRUITING

Oftalvist IMED Burjassot, Valencia

48145

RECRUITING

Augenzentrum am St. Franziskus-Hospital, Münster

50009

RECRUITING

Hospital Clínico Universitario Lozano Blesa, Zaragoza

RECRUITING

Hospital Universitario Miguel Servet, Zaragoza

50266

RECRUITING

Wolfe Eye Clinic, West Des Moines

54403

RECRUITING

Eye Clinic of Wisconsin, Wausau

55416

RECRUITING

Retina Consultants of Minnesota, Saint Louis Park

60126

RECRUITING

Retina Associates - Elmhurst Location, Elmhurst

60304

COMPLETED

Illinois Retina Associates, S.C., Oak Park

62703

RECRUITING

Springfield Clinic LLP, Springfield

72076

RECRUITING

Universitätsklinikum Tübingen, Department für Augenheilkunde, Tübingen

73013

RECRUITING

Retina Vitreous Center, Edmond

74114

RECRUITING

Tulsa Retina Consultants, Tulsa

75231

RECRUITING

Retina Foundation of the Southwest, Dallas

RECRUITING

Texas Retina Associates - Plano, Dallas

76012

RECRUITING

Texas Retina Associates- Arlington, Arlington

76087

RECRUITING

Strategic Clinical Research Group, LLC, Willow Park

76104

RECRUITING

Texas Retina Associates, Fort Worth

77384

RECRUITING

Retina Consultants of Texas, The Woodlands

77401

RECRUITING

Retina Consultants of Texas, Bellaire

77494

COMPLETED

Retina Consultants of Texas, Katy

78154

RECRUITING

Retina Consultants of Texas, Schertz

78240

RECRUITING

Retina Consultants of Texas San Antonio, San Antonio

78705

RECRUITING

Austin Research Center for Retina, Austin

RECRUITING

Austin Retina Associates, Austin

78750

RECRUITING

Austin Clinical Research, LLC, Austin

79106

RECRUITING

Southwest Retina Specialists, Amarillo

79606

RECRUITING

Retina Research Institute of Texas, Abilene

80222

RECRUITING

RSC Research, LLC, Denver

80909

RECRUITING

Retina Consultants of Southern Colorado PC, Colorado Springs

84088

RECRUITING

Salt Lake Retina, West Jordan

84107

RECRUITING

Rocky Mountain Retina Consultants, Salt Lake City

85255

RECRUITING

Retina Macula Institute of Arizona, Scottsdale

87109

RECRUITING

Vision Research Center Eye Associates of New Mexico, Albuquerque

89502

RECRUITING

Sierra Eye Associates, Reno

90211

RECRUITING

Retina-Vitreous Associates Medical Group, Beverly Hills

90503

RECRUITING

Macula Retina Vitreous Research Institute, Torrance

91204

RECRUITING

Global Research Management, Glendale

92064

COMPLETED

Retina Consultants of San Diego, Poway

92835

RECRUITING

RCOC Clinical Research Institute Inc, Fullerton

93103

COMPLETED

California Retina Consultants- Santa Barbara, Santa Barbara

94000

RECRUITING

Service d'Ophtalmologie Centre Hospitalier Intercommunal de Créteil, Créteil

94040

RECRUITING

Northern California Retina Vitreous Associates Medical Group, Inc., Mountain View

94598

RECRUITING

Bay Area Retina Associates, Walnut Creek

95356

RECRUITING

Retina Consultants Medical Group, Modesto

95825

RECRUITING

Retinal Consultants Medical Group, Sacramento

96701

RECRUITING

Retina Consultants of Hawaii, ‘Aiea

97209

RECRUITING

Eyehealth Northwest Portland, Portland

97401

RECRUITING

Verum Research, LLC, Eugene

97477

RECRUITING

Cascade Medical Research Institute, Springfield

06042

COMPLETED

Retina Consultants, P.C., Manchester

04101

RECRUITING

Maine Eye Center, Portland

02114

RECRUITING

Ophthalmic Consultants of Boston, Boston

01107

RECRUITING

Retina Research Institute at New England Retina Consultants, Springfield

07003

RECRUITING

Envision Ocular, LLC, Bloomfield

08034

RECRUITING

Mid Atlantic Retina, Cherry Hill

T2H 0C8

RECRUITING

Calgary Retina Consultants, Calgary

T5H 0X5

RECRUITING

Alberta Retina Consultants, Edmonton

N6A 4V2

RECRUITING

Ivey Eye Institute, London

K2B 7E9

RECRUITING

Retina Centre of Ottawa, Ottawa

M5T 2S8

NOT_YET_RECRUITING

Toronto Western Hospital -UHN, Toronto

100 34

RECRUITING

Fakultní nemocnice Královské Vinohrady, Prague

150 00

RECRUITING

Axon Clinical, s.r.o. Ocni Klinika, Prague

5042 AD

RECRUITING

Elisabeth Hospital (ETZ) - location TweeSteden ziekenhuis, Tilburg

85-631

RECRUITING

Oftalmika Sp.Zo.O., Bydgoszcz

10-424

RECRUITING

Centrum Diagnostyki I Mikrochirurgii Oka Lens Sp. Z O.O., Olsztyn

42-600

RECRUITING

Caminomed Sp. Z O.O., Tarnowskie Góry

01-258

RECRUITING

Warszawski Szpital Okulistyczny, Warsaw

08017

RECRUITING

Institut Català de Retina, Barcelona

08035

RECRUITING

Hospital Universitari Vall d'Hebron, Barcelona

EC1V 2PD

RECRUITING

Moorfields Eye Hospital NHS foundation Trust, London

W1G 9AX

RECRUITING

The Retina Clinic, London

All Listed Sponsors
lead

Annexon, Inc.

INDUSTRY