Impact of Combined Oral Contraceptive Pills on Migraine

PHASE4RecruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

July 15, 2024

Primary Completion Date

May 15, 2025

Study Completion Date

July 30, 2025

Conditions
Migraine
Interventions
DRUG

Combined oral contraceptive

The arm will include 200 migraine patients diagnosed according to ICHD3-beta criteria. The patients are regular users of COCs and will receive propranolol 80-160mg daily and ibuprofen 200-400 mg only in acute migraine attacks for 3 months.

DRUG

Vaginal Ring

The arm will include 200 migraine patients diagnosed according to ICHD3-beta criteria. The patients are users of mechanical contraceptive methods and will receive propranolol 80-160mg daily and ibuprofen 200-400 mg only in acute migraine attacks for 3 months.

Trial Locations (1)

33511

RECRUITING

Kafr Elsheikh University Hospital, Kafr ash Shaykh

All Listed Sponsors
lead

Kafrelsheikh University

OTHER