NCT06508710View on ClinicalTrials.gov

Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients

PHASE3RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 20, 2024

Primary Completion Date

March 31, 2026

Study Completion Date

April 30, 2026

Conditions
Major Depressive Episode
Interventions
DRUG

Ketamine

Patients randomized in this group will receive an intravenous ketamine in addition to venlafaxine for one week (on Days 1, 4 and 7)

DRUG

Placebo

Patients randomized in this group will receive an intravenous placebo in addition to venlafaxine for one week (on Days 1, 4 and 7)

Trial Locations (4)

91152

NOT_YET_RECRUITING

EPS Barthélémy Durand, Étampes

94250

NOT_YET_RECRUITING

Bicetre Hospital - CRC, Le Kremlin-Bicêtre

94270

RECRUITING

Psychiatry unit, Le Kremlin-Bicêtre

94401

ACTIVE_NOT_RECRUITING

CEA/SHFJ, Orsay

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER