NCT06506227View on ClinicalTrials.gov

Research on Key Technologies for Risk Prediction and Precise Diagnosis and Treatment of AIS Based on Epigene-phenotype

NANot yet recruitingINTERVENTIONAL
Enrollment

2,000

Participants

Timeline

Start Date

September 1, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Adolescent Idiopathic Scoliosis
Interventions
BEHAVIORAL

Low risk experimental group

Guiding + Manipulation + Traditional Chinese Medicine

BEHAVIORAL

Medium risk experimental group

Guiding + Manipulation + Traditional Chinese Medicine + Specific Exercise Therapy + Orthopedic Braces

GENETIC

High risk experimental group

Guiding + Manipulation + Traditional Chinese Medicine + Specific Exercise Therapy + Orthopedic Braces + Specialized Inpatient Rehabilitation

BEHAVIORAL

Control group COBB 10-20°

Specific Exercise Therapy

BEHAVIORAL

Control group COBB 20-45°

Orthopedic Braces + Specific Exercise Therapy

BEHAVIORAL

Control group COBB >45°

Orthopedic Braces + Specific Exercise Therapy + Recommended Surgery

OTHER

Experimental group (AIS group)

Molecular marker exploration and validation

OTHER

Control group (healthy control)

Molecular marker exploration and validation

OTHER

Controlled follow-up before and after AIS

Construction and validation of AIS risk prediction model completed

Trial Locations (1)

310006

Prokin balance apparatus, Hangzhou

All Listed Sponsors
lead

The First Affiliated Hospital of Zhejiang Chinese Medical University

OTHER