NCT06504394View on ClinicalTrials.gov

A Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) Coformulated With Berahyaluronidase Alfa (MK-3475A) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL)(MK-3475A-F65)

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 14, 2024

Primary Completion Date

November 8, 2028

Study Completion Date

November 8, 2028

Conditions
Classical Hodgkin Lymphoma RecurrentClassical Hodgkin Lymphoma RefractoryPrimary Mediastinal Large B-cell Lymphoma RecurrentPrimary Mediastinal Large B-cell Lymphoma Refractory
Interventions
BIOLOGICAL

Pembrolizumab (+) Berahyaluronidase alfa

SC injection

Trial Locations (29)

1023

COMPLETED

Auckland City Hospital ( Site 1001), Auckland

2145

COMPLETED

Westmead Hospital ( Site 0901), Westmead

11590

RECRUITING

Clinical Research Alliance ( Site 0101), Westbury

28041

RECRUITING

Hospital Universitario 12 de Octubre-Hemathology and hemotherapy ( Site 0701), Madrid

37007

RECRUITING

Hospital Universitario de Salamanca ( Site 0702), Salamanca

45147

RECRUITING

Universitaetsklinikum Essen ( Site 1302), Essen

50263

RECRUITING

University of Iowa - Waukee ( Site 0111), Waukee

52242

RECRUITING

University of Iowa-Holden Comprehensive Cancer Center ( Site 0115), Iowa City

55270

COMPLETED

Ondokuz Mayıs Universitesi ( Site 0803), Samsun

68020

RECRUITING

Centro de Investigacion Clinica de Oaxaca ( Site 0405), Oaxaca City

89169

RECRUITING

Comprehensive Cancer Centers of Nevada ( Site 0114), Las Vegas

1720430

RECRUITING

IC La Serena Research ( Site 0204), La Serena

4070196

RECRUITING

Biocenter ( Site 0203), Concepción

7500921

RECRUITING

FALP ( Site 0207), Santiago

7580206

RECRUITING

Clínica Inmunocel ( Site 0201), Santiago

8420383

RECRUITING

Bradfordhill-Clinical Area ( Site 0202), Santiago

03100

RECRUITING

Health Pharma Professional Research S.A. de C.V: ( Site 0403), Mexico City

30-727

RECRUITING

Pratia MCM Krakow ( Site 0503), Krakow

02-781

RECRUITING

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Kilinka Onkologii I Hematologii ( Site 0501), Warsaw

80-214

RECRUITING

Uniwersyteckie Centrum Kliniczne-Klinika Hematologii i Transplantologii ( Site 0502), Gdansk

44-102

RECRUITING

Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 0504), Gliwice

03080

RECRUITING

Seoul National University Hospital-Oncology ( Site 1101), Seoul

08908

RECRUITING

Institut Català d'Oncologia - L'Hospitalet-Haematology Department ( Site 0703), L'Hospitalet Del Llobregat

06100

RECRUITING

Ankara Universitesi Tıp Fakultesi Hastanesi ( Site 0801), Ankara

06230

RECRUITING

Hacettepe Universite Hastaneleri ( Site 0802), Ankara

LL18 5UJ

RECRUITING

Glan Clwyd Hospital ( Site 0602), Bodelwyddan

NW1 2PG

RECRUITING

University College London Hospital ( Site 0605), London

OX3 7LE

COMPLETED

Churchill Hospital ( Site 0604), Oxford

m20 4bx

RECRUITING

The Christie NHS Foundation Trust ( Site 0603), Manchester

All Listed Sponsors
lead

Merck Sharp & Dohme LLC

INDUSTRY