Impact of Gut Microbiota and Tryptophan Metabolites on Acute Pain in Lumbar Disc Herniation Surgery Patients

CompletedOBSERVATIONAL
Enrollment

37

Participants

Timeline

Start Date

January 12, 2022

Primary Completion Date

November 24, 2022

Study Completion Date

March 15, 2023

Conditions
Microbial SubstitutionTryptophan Metabolism AlterationsPostoperative Pain, Acute
Interventions
PROCEDURE

Pain Perception in Patients Undergoing Lumbar Disc Herniation Surgery

Analyze tryptophan metabolites (picolinic acid, 3- Hydroxykynurenine, anthranilic acid, kynurenine, quinolinic acid, kynurenic acid, xanthurenic acid). Concurrent VAS pain assessments were conducted, and correlations between tryptophan metabolites and VAS were evaluated.

Trial Locations (1)

35100

Yunu Çelik, Izmir

All Listed Sponsors
lead

Dokuz Eylul University

OTHER