Dexmedetomidine Infusion and Postoperative Lung Aeration After Thoracic Surgery

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

August 1, 2024

Primary Completion Date

March 31, 2026

Study Completion Date

August 31, 2026

Conditions
Surgery-ComplicationsRespiratory ComplicationLung Injury, Acute
Interventions
DRUG

Dexmedetomidine Hydrochloride

Initial dexmedetomidine bolus of 1 mcg/kg over 30 min after induction, followed by an infusion rate of 0.3 mcg/kg/hr that will be stopped 30-45 minutes before the end of the surgery or once a maximum dose of 2mcg/kg has been achieved, whichever comes first.

DRUG

Placebo

normal saline infusion

Trial Locations (1)

02115

RECRUITING

Brigham and Women's Hospital, Boston

All Listed Sponsors
lead

Brigham and Women's Hospital

OTHER