Contact Radiotherapy for Rectal Cancer

NARecruitingINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

March 3, 2025

Primary Completion Date

April 30, 2030

Study Completion Date

November 30, 2032

Conditions
Rectal Cancer
Interventions
RADIATION

Radiotherapy

45/50 Gy (1.8/2 Gy/fraction/5 weeks)

RADIATION

Short-course radiotherapy

25 Gy in 5 daily fractions over a total time of 1 week, treating 5 days per week, 1 fraction per day, using 5 Gy per fraction, over the maximum treatment period of eight calendar days

RADIATION

Contact x-ray brachytherapy

90Gy/3 fractions/4 weeks

DRUG

Chemotherapy

Capecitabine (900 mg/m2 bid, on radiation days)

Trial Locations (2)

171 76

RECRUITING

Karolinska University Hospital, Theme Cancer, Dept of Pelvic cancer, Stockholm

751 85

RECRUITING

Uppsala University Hospital, Colorectal Surgery, Uppsala

All Listed Sponsors
collaborator

Uppsala University Hospital

OTHER

collaborator

Karolinska Institutet

OTHER

lead

Alexander Valdman

OTHER