Visual Involvement in Giant Cell Arteritis

RecruitingOBSERVATIONAL
Enrollment

762

Participants

Timeline

Start Date

June 27, 2024

Primary Completion Date

June 30, 2028

Study Completion Date

June 30, 2030

Conditions
Giant Cell ArteritisVisual ImpairmentCentral Retinal Artery OcclusionAnterior Ischemic Optic NeuropathyParacentral Acute Middle MaculopathyPosterior Ischemic Optic NeuropathyRetinal IschemiaBlindnessVisual Disorder
Interventions
DIAGNOSTIC_TEST

Fluorescein and Indocyanine green Angiography

The ophthalmologist frequently recommends fluorescein (FAG) and indocyanine green angiography (ICGA) at baseline (T0) to evaluate retinal and choroidal vascularisation. They can be repeated also after 48-72 hours (T1), 7 ± 2 days (T2), 4 ± 1 weeks (T3), 12 ± 2 weeks (T4) or 26 ± 2 weeks (T5).

DIAGNOSTIC_TEST

High-resolution Optical Coherence Tomography

The ophthalmologist often suggests performing HR-OCT initially (T0) to assess the width of the macula and optic nerve with potential signs of ischemic lesions in these areas. This assessment can also be repeated after 48-72 hours (T1), 7 ± 2 days (T2), 4 ± 1 weeks (T3), 12 ± 2 weeks (T4), or 26 ± 2 weeks (T5).

DIAGNOSTIC_TEST

Angio-Optical Coherence Tomography

The ophthalmologist often suggests OCT-A at the beginning (T0) to assess the retinal and choroidal vascularization. These tests can also be done after 48-72 hours (T1), 7 ± 2 days (T2), 4 ± 1 weeks (T3), 12 ± 2 weeks (T4), or 26 ± 2 weeks (T5).

Trial Locations (1)

20157

RECRUITING

ASST Fatebenefratelli-Sacco, Milan

All Listed Sponsors
lead

ASST Fatebenefratelli Sacco

OTHER