Instrumental Respiratory Physiotherapy in Difficult-to-wean ICU Patients

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

March 18, 2025

Primary Completion Date

March 1, 2027

Study Completion Date

May 1, 2027

Conditions
Ventilator Weaning
Interventions
PROCEDURE

Systematic and early intensive instrumental respiratory physiotherapy for patients undergoing difficult ventilatory weaning

Patients randomized to this group will receive 3 sessions per day of intensive early respiratory physiotherapy with instrumental techniques from randomization to day 7, before and after any extubation. The strategy will be applied until day 7 of randomization, regardless of the patient's status (intubated or not).

PROCEDURE

Protocolized standard-of-care respiratory physiotherapy

Patients in this group will receive standardized and protocolized respiratory physiotherapy to reproduce the usual practices of non-expert centers,1 to 2 sessions of manual respiratory physiotherapy (not assisted by an instrumental technique) per day until the day of successful extubation, or until day 7 if necessary

Trial Locations (2)

69004

RECRUITING

Médecine Intensive - Réanimation, Hôpital de la Croix Rousse, Lyon

69495

NOT_YET_RECRUITING

Département d'Anesthésie Réanimation - Médecine Intensive, Centre Hospitalier Lyon Sud, Lyon

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER