Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

August 31, 2024

Primary Completion Date

June 30, 2025

Study Completion Date

December 31, 2025

Conditions
Extensive-Stage Small Cell Lung Cancer
Interventions
DRUG

Serplulimab

"Serplulimab will be administered intravenously at a dose of 4.5 mg/kg on Day 1 of each 21-day cycle for 4 cycles in the induction phase.~Serplulimab will be administered intravenously at a dose of 4.5 mg/kg on Day 1 of each 21-day cycle in the maintenance phase."

DRUG

Lurbinectedin

Lurbinectedin will be administered intravenously at a fixed dose of 4 mg on Day 1 of each 21-day cycle in the maintenance phase.

DRUG

Carboplatin

Carboplatin will be administered according to the standard of care treatment for 4 cycles in the induction phase.

DRUG

Etoposide

Etoposide will be administered according to the standard of care treatment for 4 cycles in the induction phase.

All Listed Sponsors
lead

Guangzhou Institute of Respiratory Disease

OTHER