Antidepressant Adherence for Depressed Adults in Primary Care

NARecruitingINTERVENTIONAL
Enrollment

525

Participants

Timeline

Start Date

March 19, 2025

Primary Completion Date

March 31, 2029

Study Completion Date

March 31, 2029

Conditions
Depression
Interventions
BEHAVIORAL

Reminders

We will send daily text messages to participants for 12 weeks reminding them to take their antidepressant medication. These reminders will be tailored, personalized and patient-centric, grounded in behavioral economics principles.

BEHAVIORAL

Incentives

In addition to daily text messages, participants will receive financial incentives for 6 weeks based on contingency management principles. Participants assigned to the Reminders and Incentives arm of the study will receive a $2/day incentive, increasing by $1/day conditioned on each week that they consistently take their antidepressant over the first 6 weeks, for a maximum total payment of $189 ($2, $3, $4, $5, $6, $7 in weeks 1 through 6, respectively).

Trial Locations (1)

19104

RECRUITING

University of Pennsylvania Health System, Philadelphia

All Listed Sponsors
lead

University of Pennsylvania

OTHER