Standard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response (PEACE6-Poor Responders)

PHASE3RecruitingINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

September 12, 2024

Primary Completion Date

February 1, 2033

Study Completion Date

August 1, 2039

Conditions
Prostate Cancer Metastatic
Interventions
DRUG

177Lu-PMSA-617

Once every 6 weeks, 7400 MBq 177Lu-PMSA-617 will be administered for up to a total of 4 cycles.

DRUG

Standard of Care

ADT, abiraterone and each ARSI (Apalutamide, Darolutamide, Enzalutamide) will be administrated according to the standard of care

Trial Locations (25)

Unknown

NOT_YET_RECRUITING

Institut de Cancérologie de l'Ouest, Angers

NOT_YET_RECRUITING

Institut Bergonié, Bordeaux

NOT_YET_RECRUITING

CHRU Brest, Brest

NOT_YET_RECRUITING

Centre Francois Baclesse, Caen

NOT_YET_RECRUITING

CHU Henri Mondor, Créteil

NOT_YET_RECRUITING

Centre Georges-François Leclerc, Dijon

NOT_YET_RECRUITING

CHU Grenoble, Grenoble

NOT_YET_RECRUITING

Centre Léon Berard, Lyon

RECRUITING

Institut Paoli-Calmettes, Marseille

NOT_YET_RECRUITING

CHRU Nancy, Nancy

NOT_YET_RECRUITING

Centre Antoine Lacassagne, Nice

NOT_YET_RECRUITING

Hôpital Cochin, Paris

NOT_YET_RECRUITING

Hôpital Saint Louis, Paris

NOT_YET_RECRUITING

Institut Curie, Paris

RECRUITING

Centre Eugène Marquis, Rennes

NOT_YET_RECRUITING

Centre Henri Becquerel, Rouen

NOT_YET_RECRUITING

CHU Rouen, Rouen

NOT_YET_RECRUITING

Institut Curie, Saint-Cloud

NOT_YET_RECRUITING

Institut de Cancérologie de l'Ouest, Saint-Herblain

NOT_YET_RECRUITING

CHU Saint Etienne, Saint-Priest-en-Jarez

NOT_YET_RECRUITING

ICANS, Strasbourg

NOT_YET_RECRUITING

IUCT Oncopole, Toulouse

NOT_YET_RECRUITING

CHRU Tours, Tours

NOT_YET_RECRUITING

Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy

RECRUITING

Gustave Roussy, Villejuif

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

lead

UNICANCER

OTHER

NCT06496581 - Standard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response (PEACE6-Poor Responders) | Biotech Hunter | Biotech Hunter