Bendamustine and Rituximab With or Without Orelabrutinib in MCL Treatment

PHASE3RecruitingINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

July 10, 2024

Primary Completion Date

July 10, 2027

Study Completion Date

July 10, 2027

Conditions
Mantle Cell Lymphoma (MCL)
Interventions
DRUG

Orelabrutinib

Orelabrutinib PO will be administered as per the schedule specified in the respective arm.

DRUG

Bendamustine

Bendamustine IV will be administered as per the schedule specified in the respective arm.

DRUG

Rituximab

Rituximab IV will be administered as per the schedule specified in the respective arm.

DRUG

Venetoclax

Venetoclax PO will be administered as per the schedule specified in the respective arm.

Trial Locations (1)

200025

RECRUITING

Ruijin Hospital, Shanghai

All Listed Sponsors
collaborator

Third Xiangya Hospital of Central South University

UNKNOWN

collaborator

Anhui Provincial Cancer Hospital

OTHER

collaborator

Fujian Medical University Union Hospital

OTHER

collaborator

Yantai Yuhuangding Hospital

OTHER

collaborator

Huadong Hospital Affiliated with Fudan University, Shanghai

UNKNOWN

collaborator

The First Affiliated Hospital of Anhui Medical University

OTHER

collaborator

Jiangxi Provincial Cancer Hospital

OTHER

collaborator

Fujian Cancer Hospital

OTHER_GOV

lead

Ruijin Hospital

OTHER