Mechanical Power As a Predictor for Weaning in Chronic Obstructive Pulmonary Disease Patients :Prospective Cohort Study.

Not yet recruitingOBSERVATIONAL
Enrollment

84

Participants

Timeline

Start Date

December 1, 2024

Primary Completion Date

August 1, 2026

Study Completion Date

August 1, 2026

Conditions
Mechanical Power
Interventions
OTHER

Chest ultrasound

to assess diaphragmatic excursion (DE(. M-mode was used to record the movement of the diaphragm during tidal breathing when the sampling line and diaphragm were as vertical as possible (not \< 70°). The data was measured from the first respiratory cycle at 0 min after SBT.

OTHER

Calculation of Mechanical Power on the first day of intubation and before First trial of weaning:

"Total respiratory rate (RR). Positive end-expiratory pressure (PEEP) (the external or applied PEEP) recorded, not the total PEEP, or intrinsic PEEP. The plateau pressure (Pplat) was measured during an inspiratory pause on the ventilator. Peak inspiratory pressure (Ppeak) should be obtained while the patient is relaxed, not coughing or moving in bed. MP was calculated according to Gattinoni's simplified mechanical power equation as follows (3,8):~MP(J/min)=0.098×VT×RR×(Ppeak-0.5×ΔP)."

Trial Locations (1)

Unknown

Assiut University, Asyut

All Listed Sponsors
lead

Assiut University

OTHER

NCT06493929 - Mechanical Power As a Predictor for Weaning in Chronic Obstructive Pulmonary Disease Patients :Prospective Cohort Study. | Biotech Hunter | Biotech Hunter