Evaluation of a Differentiated Point-of-care Active Case Finding & Management Model to Eliminate Mother-to-Child Transmission of HIV in Malawi

NARecruitingINTERVENTIONAL
Enrollment

2,426

Participants

Timeline

Start Date

March 27, 2025

Primary Completion Date

January 31, 2028

Study Completion Date

January 31, 2028

Conditions
HIV Prevention
Interventions
BEHAVIORAL

PAC-Man

"PAC-Man represents an integrated DSD model for mothers and infants that brings the following three evidence-based practices into the community for EMTCT: 1) pediatric active case finding using novel POC EID technology; 2) same-day ART initiation for infants newly diagnosed with HIV infection; and 3) mVL testing and back-to-care services. PAC-Man uses a mobile approach to offer EMTCT services in the community and reach high risk MIPs. Delivering the PAC-Man model will be done under the auspices of routine care, applying an overarching implementation strategy of creating new mobile care teams equipped with new diagnostic technology who deploy the m-PIMA in community settings."

BEHAVIORAL

Standard of Care

Routine care as provided by Ministry of Health.

Trial Locations (3)

Unknown

NOT_YET_RECRUITING

Bwaila Hospital, Lilongwe

RECRUITING

Area 18 Health Centre, Lilongwe

RECRUITING

Monkey Bay Community Hospital, Monkey Bay

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

University of North Carolina, Chapel Hill

OTHER