NCT06491394 - Lactoferrin Effect on Kidney and Heart of Rhabdomyolysis Rats | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 1, 2024

Primary Completion Date

March 1, 2025

Study Completion Date

April 1, 2025

Conditions

Rhabdomyolysis

Interventions

DRUG

Lactoferrin

an iron-binding protein

DIAGNOSTIC_TEST

iron

Iron in kidney and heart tissues

DIAGNOSTIC_TEST

MDA, TAC, and GSH

Oxidative stress levels in kidney and heart tissues

DIAGNOSTIC_TEST

Nrf2

Nrf2 expression in kidney and heart tissues

DIAGNOSTIC_TEST

AMPK

AMPK levels in heart and kidney tissues

DIAGNOSTIC_TEST

HO-1

HO-1 levels in kidney and heart tissues

DRUG

glycerin

GLY intramuscular injection for rhabdomyolysis induction

Trial Locations (1)

Faculty of Medicine, Aswān

All Listed Sponsors

lead

Aswan University Hospital

OTHER