NCT06489626View on ClinicalTrials.gov

The Effect of a Methylprednisolone Taper on Outcomes Following Total Knee Arthroplasty

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

November 1, 2025

Primary Completion Date

October 1, 2027

Study Completion Date

December 1, 2027

Conditions
Arthritis KneeKnee OsteoarthritisPain, Postoperative
Interventions
DRUG

Methylprednisolone 4 milligram Tab

6-day 4 milligram methylprednisolone oral taper

DRUG

Dexamethasone injection

4 milligram intravenous dexamethasone will be administered intraoperatively

Trial Locations (2)

15146

UPMC East, Monroeville

15232

UPMC Shadyside Hospital, Pittsburgh

All Listed Sponsors
lead

F. Johannes Plate

OTHER