Comparing Two Doses of Oral Melatonin as Premedication in Children Undergoing Surgery

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

July 12, 2024

Primary Completion Date

December 15, 2024

Study Completion Date

December 15, 2024

Conditions
Preoperative Anxiety
Interventions
DRUG

melatonin (Circadin ®) 0.2 mg/kg

Patients will receive oral melatonin at a dose of 0.2 mg/kg as premedication in the morning of the surgery, 90 minutes before the induction of anesthesia, with a maximum dose of melatonin set at 10 mg.

DRUG

melatonin (Circadin ®) 0.4 mg/kg

Patients will receive oral melatonin at a dose of 0.4 mg/kg as premedication in the morning of the surgery, 90 minutes before the induction of anesthesia, with a maximum dose of melatonin set at 10 mg.

DRUG

placebo group

Patients will receive oral placebo as premedication in the morning of the surgery, 90 minutes before the induction of anesthesia, with a maximum dose of melatonin set at 10 mg.

Trial Locations (2)

11765

RECRUITING

Facualty of Pharmacy, Al Azhar University, Cairo

51015

RECRUITING

Al-Ayen Univerisity, Madīnat Bābil

All Listed Sponsors
collaborator

Al-Ayen Iraqi University

OTHER

lead

Al-Azhar University

OTHER