Remineralizing Effect of Different Silver-containing Agents on Initial Caries Lesions in Primary Teeth in Children

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

July 29, 2024

Primary Completion Date

May 31, 2025

Study Completion Date

June 30, 2025

Conditions
White Spot Lesion of Tooth
Interventions
DRUG

NSF

Prior to treatment the working field is isolated with cotton rolls. Gingival barrier is used for soft tissue protection. Application of NSF using a microapplicator on the carious lesion for 1 minute. Excess material and gingival barrier are removed. Participants receive oral hygiene instructions.

DRUG

SDF+KI

Prior to treatment the working field is isolated with cotton rolls. Gingival barrier is used for soft tissue protection. Application of 38% silver diamine fluoride (Riva star 38%, SDI) using a microapplicator on the carious lesion. Immediately afterwards, potassium iodide is applied as a reducing agent. Excess material and gingival barrier are removed. Participants receive oral hygiene instructions.

OTHER

Control group

Subjects will receive oral hygiene instructioins to apply fluoridated toothpaste to a toothbrush and brush teeth thoroughly for at least 2 minutes, then expectorate and rinse.

Trial Locations (1)

4000

RECRUITING

Department of Pediatric Dentistry, Faculty of Dental Medicine, Medical University-Plovdiv, Plovdiv

All Listed Sponsors
lead

Plovdiv Medical University

OTHER