Outcome and Improvement of Different Treatment in Arteriosclerosis Obliterans

RecruitingOBSERVATIONAL
Enrollment

400

Participants

Timeline

Start Date

July 1, 2024

Primary Completion Date

July 31, 2026

Study Completion Date

July 31, 2029

Conditions
Arteriosclerosis Obliterans
Interventions
PROCEDURE

open bypass group

After heparinization, the target artery is clamped above and below the anastomosis. The target artery is dissected along the anterior wall, calcium portions or mural thrombus are removed. Graft (autologous or prosthetic graft) is cut obliquely and anastomosis suturing starts with distal angle. Next stage is tunnel creating for graft conduction.

PROCEDURE

bare metal stent group

Bare metal stent implantation during the index procedure.

PROCEDURE

plain old balloon angioplasty group

Only plain old balloon was used during the index procedure.

PROCEDURE

drug-coated balloon group

Drug-coated balloon was used during the index procedure.

PROCEDURE

directional atherectomy group

Directional atherectomy (with or without drug-coated balloon) during the index procedure.

PROCEDURE

hybrid repair group

Femoral artery arteriotomy. Further execute a direct endarterectomy femoral artery and from the mouth of a hip artery. Arteriotomy of the femoral artery is closed with a vascular patch use (synthetic or biological). Endovascular revascularization followed.

Trial Locations (1)

510030

RECRUITING

The First Affiliated Hospital of Sun Yat-sen University, Guangzhou

All Listed Sponsors
lead

First Affiliated Hospital, Sun Yat-Sen University

OTHER