Safety and Efficacy of Selective Intra-Arterial Cooling Infusion Combined With EVT in Acute Ischemic Stroke

NARecruitingINTERVENTIONAL
Enrollment

258

Participants

Timeline

Start Date

July 3, 2024

Primary Completion Date

June 1, 2026

Study Completion Date

August 1, 2026

Conditions
Acute Ischemic StrokeHypothermia
Interventions
PROCEDURE

Selective Intra-arterial Cooling Infusion (IA-SCI)

"Pre-recanalization: During the procedure, the micro-catheter is advanced over a micro-guide wire, traveling up through the neck until it reaches beyond the clot. A 50 mL cold 0.9% saline (4 ℃) is infused intro into the ischemic territory at a rate of 10 mL/min via the micro-catheter. This enables the cold solution to infuse into the ischemic territory prior to revascularization.~Post-recanalization: After recanalization, cold 0.9% saline (4 ℃) is reinfused into the vessel via the catheter at a rate of 22 mL/min for 10 min, repeated twice with a 10-minute interval between infusions."

Trial Locations (9)

Unknown

RECRUITING

The Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou

RECRUITING

Department of Neurosurgery, Nanshi Hospital of Nanyang, Nanyang

RECRUITING

The Affiliated Hospital of Xuzhou Medical University, Xuzhou

RECRUITING

Beijing Shijitan Hospital, Capital Medical University, Beijing

RECRUITING

Peking University Internation Hospital, Beijing

RECRUITING

967 Hospital of the Joint Logistics Support Force of PLA, Dalian

RECRUITING

Dalian Municipal Central Hospital, Dalian

RECRUITING

The First Affiliated Hospital of Harbin Medical University, Ha’erbin

RECRUITING

Affiliated Hospital of Inner Mongolia University for the Nationalities, Tongliao

All Listed Sponsors
lead

Beijing Shijitan Hospital, Capital Medical University

OTHER