Comparison of Isotonic Versus Hypotonic Fluids in Neonates for Maintenance Fluid Therapy After Surgery

NACompletedINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

January 1, 2023

Primary Completion Date

December 29, 2023

Study Completion Date

December 29, 2023

Conditions
HyponatremiaHypernatremiaPostoperative Care in NeonatesEdema
Interventions
DRUG

Isotonic Saline with Dextrose

This clinical trial involves two interventions for maintaining fluid therapy in neonates post-surgery. The first intervention, isotonic saline with dextrose, involves administering 0.9% saline solution combined with 5% dextrose. This isotonic solution aims to maintain serum sodium levels within the normal range and minimize the risk of hyponatremia and hypernatremia in postoperative neonates. The second intervention, hypotonic saline with dextrose, involves administering 0.45% saline solution combined with 5% dextrose. This hypotonic solution is being compared to the isotonic solution to evaluate its effectiveness in maintaining electrolyte balance.

Trial Locations (1)

00042

Mehak Fatima, Rawalpindi

All Listed Sponsors
lead

Rawalpindi Medical College

OTHER