Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy Volunteers

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

February 21, 2025

Primary Completion Date

August 31, 2027

Study Completion Date

August 31, 2027

Conditions
Irritability
Interventions
OTHER

Frustration task

The experimental manipulation for this study is the frustration task. The frustration task is designed to elicit the emotional state of frustrative non-reward (FNR). During the task, participants are asked to use button press (left or right) to alternately press one of the two doors displayed on the monitor. The task has two non-frustration blocks (Block 1 and 2) and one frustration block (Block 3). During the non-frustration blocks, participants earn money for correct press on a fixed schedule. During the frustrative block, participants will not always receive reward for correct press.

Trial Locations (2)

20892

RECRUITING

National Institutes of Health Clinical Center, Bethesda

77843

NOT_YET_RECRUITING

Texas A&M University, College Station

All Listed Sponsors
lead

National Institute of Mental Health (NIMH)

NIH