Novel Treatments in Improving Renal Outcomes in Light Chain Cast Nephropathy

RecruitingOBSERVATIONAL
Enrollment

450

Participants

Timeline

Start Date

June 1, 2024

Primary Completion Date

June 1, 2025

Study Completion Date

June 1, 2026

Conditions
Multiple MyelomaLight Chain NephropathyAcute Kidney Injury
Interventions
PROCEDURE

Plasma exchange

Patients treated with plasma exchange within 30 days of diagnosis of light chain cast nephropathy Patients not treated with daratumumab within 30 days of diagnosis of light chain cast nephropathy

DRUG

Daratumumab

Patients treated with daratumumab within 30 days of diagnosis of light chain cast nephropathy

Trial Locations (1)

02130

RECRUITING

Brigham and Women's Hospital, Boston

All Listed Sponsors
collaborator

Janssen, LP

INDUSTRY

collaborator

Baystate Health

OTHER

collaborator

Boston Medical Center

OTHER

collaborator

Dana-Farber Cancer Institute

OTHER

collaborator

Massachusetts General Hospital

OTHER

collaborator

Mayo Clinic

OTHER

collaborator

M.D. Anderson Cancer Center

OTHER

collaborator

Medical University of South Carolina

OTHER

collaborator

H. Lee Moffitt Cancer Center and Research Institute

OTHER

collaborator

Icahn School of Medicine at Mount Sinai

OTHER

collaborator

Northwell Health

OTHER

collaborator

Ochsner Health System

OTHER

collaborator

Ohio State University

OTHER

collaborator

Stanford University

OTHER

collaborator

Texas Medical Center

UNKNOWN

collaborator

Thomas Jefferson University

OTHER

collaborator

University of Alabama at Birmingham

OTHER

collaborator

University of California, Los Angeles

OTHER

collaborator

University of Chicago

OTHER

collaborator

University of Colorado Health

OTHER

collaborator

University of Minnesota

OTHER

collaborator

University of New Mexico

OTHER

collaborator

University of Pennsylvania

OTHER

collaborator

University of Pittsburgh

OTHER

collaborator

University of Virginia

OTHER

collaborator

University of Washington

OTHER

lead

Brigham and Women's Hospital

OTHER