Safety and Efficacy of Different Procedures of Colpocleisis: a Randomized Controlled Trial

NANot yet recruitingINTERVENTIONAL
Enrollment

330

Participants

Timeline

Start Date

July 31, 2024

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2027

Conditions
Pelvic Organ Prolapse
Interventions
PROCEDURE

total colpocleisis

Total colpocleisis refers to the process where, during the dissection of the anterior and posterior vaginal walls to remove the vaginal mucosa, no holes are left. When suturing, the anterior and posterior vaginal walls are completely interrupted with mattress sutures, and no holes are left on either side or at the top of the vagina.

PROCEDURE

partial colpocleisis (LeFort)

LeFort involves the removal of a rectangular piece of mucosa from the anterior and posterior walls of the vagina, leaving a strip of mucosa 2 to 3 cm wide on each side of the vagina. The dissection is carried out close to the vaginal mucosa while preserving the vaginal bladder fascia as much as possible, creating channels on both sides of the vagina.

All Listed Sponsors
lead

Lan Zhu

OTHER

NCT06482697 - Safety and Efficacy of Different Procedures of Colpocleisis: a Randomized Controlled Trial | Biotech Hunter | Biotech Hunter