730
Participants
Start Date
December 1, 2024
Primary Completion Date
December 1, 2029
Study Completion Date
December 1, 2034
Blood Sampling (2*8mL Tubes)
Patients will be sampled from 2 x 8 mL blood tubes (EDTA tubes)
PBMC Sampling (1*8mL Tubes)
Patients will be sampled from 1 x 8 mL PBMC
Paxgene Sampling
Patients will be sampled from 1 x 8 mL of blood with Paxgene Tube
Extended biopsies of tumor lesions
"Regarding the ancillary study, as part of the care, patients are biopsied at diagnosis and during relapse(s). For metastatic patients with multiple sites, one site (the most accessible) is chosen and biopsied in interventional radiology or pulmonology.~The material used is: 17-18G biopsy needle / Sampling chamber volume of 0.01 cm³ to 0.02 cm³.~For a standard biopsy as part of the care, 3 samples are taken (total volume of 0.03 cm³ to 0.06 cm³). Inclusion in the ancillary study would add one sample using the same biopsy path, resulting in an additional volume of 0.01 cm³ to 0.02 cm³.~In the case of a complex biopsy, no additional sampling related to the research will be performed."
Nantes University Hospital
OTHER