Adebrelimab Plus Apatinib for Maintenance Therapy of Extensive Stage Small Cell Lung Cancer

NARecruitingINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

August 9, 2024

Primary Completion Date

August 31, 2025

Study Completion Date

August 31, 2026

Conditions
Small Cell Lung Cancer
Interventions
DRUG

Adebrelimab Injection

Adebrelimab injection (1200mg) will be administered by intravenous infusion during the induction phase and maintenance phase on day 1 in a 3-week treatment cycle.

DRUG

Apatinib Mesylate Tablets

Apatinib mesylate tablets (250 mg) will be administered orally in a 3-week treatment cycle, once a day.

DRUG

Carboplatin

Carboplatin (AUC 4-5mg/mL/min) intravenous infusion will be administered during the induction phase on day 1 in a 3-week treatment cycle.

DRUG

Cisplatin

Cisplatin (75mg/m2) intravenous infusion will be administered during the induction phase on day 1 in a 3-week treatment cycle.

DRUG

Etoposide

Etoposide(100mg/m2) intravenous infusion will be administered during the induction phase from day 1 to 3 in a 3-week treatment cycle.

Trial Locations (2)

110000

NOT_YET_RECRUITING

The First Hospital of China Medical University, Shenyang

110002

RECRUITING

The First Hospital of China Medical University, Shenyang

All Listed Sponsors
collaborator

Jiangsu HengRui Medicine Co., Ltd.

INDUSTRY

lead

Yunpeng Liu

OTHER