40
Participants
Start Date
January 15, 2026
Primary Completion Date
December 31, 2026
Study Completion Date
May 31, 2027
Ketogenic diet
The ketogenic diet consisting of fats (70%), protein (20%) and carbohydrates (10%) will be consumed for 14 days prior to undergoing open-heart surgery, and up to 6 days postoperatively or until discharge (if within 6 days postoperatively).
Control diet
The control diet consisting of a Mediterranean diet, at 25% fat, 20% protein and 55% carbohydrates will be consumed for 14 days prior to undergoing open-heart surgery, and up to 6 days postoperatively or until discharge (if within 6 days postoperatively).
University on Missouri Hospital, Columbia
National Institutes of Health (NIH)
NIH
University of Missouri-Columbia
OTHER