200
Participants
Start Date
August 1, 2024
Primary Completion Date
April 1, 2026
Study Completion Date
April 30, 2026
Continuous Laryngoscopy during Exercise Test (CLE test)
A flexible fiberoptic laryngoscope (Olympus, Tokyo, Japan) is introduced directly through the nose or via a slightly modified Hans Rudolph facemask, and into the pharyngeal space. A modified Bruce protocol with a 60-second incremental intensity step is used (Appendix A) and heart rate is monitored. During the CLE test participants perform incremental exercise on a treadmill until symptom-limiting distress or exhaustion. Forced expiratory flow-volume loops are measured before, during and after the CLE test.
Medisch Spectrum Twente, Enschede
Haukeland University Hospital
OTHER
Medisch Spectrum Twente
OTHER