Prevalence of EILO Among Children With Asthma

NANot yet recruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

August 1, 2024

Primary Completion Date

April 1, 2026

Study Completion Date

April 30, 2026

Conditions
Exercise Induced Laryngeal ObstructionAsthma in ChildrenExercise-Induced BronchospasmExercise-Induced BronchoconstrictionDyspneaLarynx
Interventions
DIAGNOSTIC_TEST

Continuous Laryngoscopy during Exercise Test (CLE test)

A flexible fiberoptic laryngoscope (Olympus, Tokyo, Japan) is introduced directly through the nose or via a slightly modified Hans Rudolph facemask, and into the pharyngeal space. A modified Bruce protocol with a 60-second incremental intensity step is used (Appendix A) and heart rate is monitored. During the CLE test participants perform incremental exercise on a treadmill until symptom-limiting distress or exhaustion. Forced expiratory flow-volume loops are measured before, during and after the CLE test.

Trial Locations (1)

7512 KZ

Medisch Spectrum Twente, Enschede

All Listed Sponsors
collaborator

Haukeland University Hospital

OTHER

lead

Medisch Spectrum Twente

OTHER

NCT06480084 - Prevalence of EILO Among Children With Asthma | Biotech Hunter | Biotech Hunter