Early Resuscitation in Paediatric Sepsis Using Inotropes

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

July 31, 2024

Primary Completion Date

July 31, 2025

Study Completion Date

December 31, 2025

Conditions
Sepsis
Interventions
OTHER

Fluid

Sepsis will be treated with standardized therapy protocol, where participants receive fluids (balanced or non-balanced crystalloids, or colloids) to be resuscitated. Specifically, they will receive 40-60 ml/kg of fluids before the initiation of inotropes.

DRUG

Adrenalin

Sepsis will be treated with early inotropes, where participants will receive adrenaline at a dose of 0.05 - 0.1 mcg/kg/min via peripheral intravenous, intraosseous, or central venous routes after the first fluid bolus of 20 ml/kg

Trial Locations (4)

Unknown

"Hospital de Niños Dr. Orlando Alassia", Santa Fe

Hospital Regional San Juan De Dios Tarija, Tarija

Hospital De Clínicas, Asunción

Hospital Niños de Acosta Ñu, San Lorenzo

All Listed Sponsors
collaborator

University Children's Hospital, Zurich

OTHER

collaborator

Universidad Nacional del Nordeste, Argentina

OTHER

collaborator

Instituto Latino Americano de Sepse

UNKNOWN

collaborator

Hospital Pablo Tobón Uribe

OTHER

lead

NATALIA LOPERA MUNERA

OTHER