ADDICTOlogical Intervention in LIVEr Transplantation Recipients

NARecruitingINTERVENTIONAL
Enrollment

720

Participants

Timeline

Start Date

November 21, 2024

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2028

Conditions
Alcohol Associated Liver DiseaseLiver Transplantation
Interventions
OTHER

Post-transplant addiction intervention

The first addiction consultation will be conducted using the BRENDA method which allows the addiction specialist to carry out a psychosocial assessment, to entrust the results of this assessment to the participant, to answer their questions and to evaluate their reactions. Risk factors for alcohol relapse will be collected: social determinants, male gender, psychiatric comorbidities, duration of alcohol abstinence before LT(≥ or \< 6 months) and young age (\< 40 years). If the addiction specialist notes the presence of at least 3 risk factors for alcohol relapse, targeted addiction follow-up will be proposed to the participant including outpatient consultations with motivational interview at least every 4 weeks +/- pharmacological treatment of alcohol use disorder.In case of alcohol relapse or a period of high vulnerability to relapse, specific hospitalizations can be scheduled. If the participant has \<3 risk factors, an addictology consultation every 6 months at most will be proposed.

Trial Locations (17)

34000

RECRUITING

Montpellier University Hospital, Montpellier

Unknown

NOT_YET_RECRUITING

Besançon University Hospital, Besançon

NOT_YET_RECRUITING

Bordeaux University Hospital, Bordeaux

RECRUITING

Clermont Ferrand University Hospital, Clermont-Ferrand

NOT_YET_RECRUITING

Dijon University Hospital, Dijon

NOT_YET_RECRUITING

Grenoble University Hospital, Grenoble

NOT_YET_RECRUITING

Lille University Hospital, Lille

RECRUITING

Lyon University Hospital, Lyon

NOT_YET_RECRUITING

Marseille University Hospital, Marseille

NOT_YET_RECRUITING

Nice University Hospital, Nice

NOT_YET_RECRUITING

APHP Mondor, Paris

NOT_YET_RECRUITING

APHP Paul Brousse, Paris

NOT_YET_RECRUITING

APHP Salpetrière, Paris

NOT_YET_RECRUITING

Rennes University Hospital, Rennes

RECRUITING

Strasbourg University Hospital, Strasbourg

NOT_YET_RECRUITING

Toulouse University Hospital, Toulouse

NOT_YET_RECRUITING

Tours University Hospital, Tours

All Listed Sponsors
lead

University Hospital, Montpellier

OTHER