NCT06471465View on ClinicalTrials.gov

Corticodependent or Corticoresistant Brain Radionecrosis After Radiotherapy for Brain Metastases

PHASE3RecruitingINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

April 29, 2025

Primary Completion Date

August 31, 2028

Study Completion Date

August 31, 2030

Conditions
Radionecrosis of BrainBrain Metastases
Interventions
DRUG

Bevacizumab

Drug: bevacizumab IV

DRUG

Placebo

Drug: placebo IV

DRUG

Prednisolone

Drug: corticosteroids IV

Trial Locations (10)

14000

RECRUITING

Centre Francois Baclesse, Caen

21079

NOT_YET_RECRUITING

Centre Georges François Leclerc, Dijon

29609

RECRUITING

CHRU de Brest, Brest

35042

RECRUITING

Centre Eugène marquis, Rennes

37170

RECRUITING

Centre D'Oncologie Et de Radiotherapie 37, Chambray-lès-Tours

44805

RECRUITING

Institut de Cancérologie de l'Ouest, Saint-Herblain

56000

RECRUITING

Centre Saint Yves, Vannes

67000

RECRUITING

Centre Paul Strauss, Strasbourg

69373

RECRUITING

Centre Léon Bérard, Lyon

76600

RECRUITING

Centre Guillaume le Conquérant, Le Havre

All Listed Sponsors
lead

Institut Cancerologie de l'Ouest

OTHER