NCT06467292View on ClinicalTrials.gov

Speech Motor Learning and Retention (Master Protocol)

NARecruitingINTERVENTIONAL
Enrollment

330

Participants

Timeline

Start Date

October 1, 2024

Primary Completion Date

November 30, 2028

Study Completion Date

May 31, 2029

Conditions
Speech
Interventions
DEVICE

continuous theta-burst stimulation (cTBS)

cTBS stimulation will be applied to different areas of the brain following learning. Stimulation will take place following learning in order to block motor memory retention.

BEHAVIORAL

Adaptation

Auditory adaptation in speech

DEVICE

Single pulse Transcranial magnetic stimulation (TMS)

TMS will be delivered 10 times in each motor evoked potentials (MEP) recording block.

DEVICE

fMRI

To assess functional connectivity patterns between regions that predict learning.

Trial Locations (1)

06520

RECRUITING

Yale Child Study Center, New Haven

All Listed Sponsors
collaborator

National Institute on Deafness and Other Communication Disorders (NIDCD)

NIH

lead

Yale University

OTHER