Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline

NACompletedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

May 30, 2024

Primary Completion Date

April 10, 2025

Study Completion Date

May 29, 2025

Conditions
Middle-aged AdultsMajor Depressive Disorder
Interventions
DRUG

MitoTempol

One intradermal microdialysis probes will be perfused with MitoTempol (0.5 mM) during a standard local skin heating protocol.

DRUG

Lactated Ringer's (control)

One intradermal microdialysis probes will be perfused with lactated Ringer's (control) during a standard local skin heating protocol.

Trial Locations (1)

19713

University of Delaware, Newark

All Listed Sponsors
collaborator

National Institute of General Medical Sciences (NIGMS)

NIH

lead

University of Delaware

OTHER