OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT)

NARecruitingINTERVENTIONAL
Enrollment

302

Participants

Timeline

Start Date

April 15, 2025

Primary Completion Date

February 15, 2029

Study Completion Date

February 15, 2029

Conditions
Breast CancerProstate CancerNSCLCColorectal CancerOligometastatic Disease
Interventions
RADIATION

single-fraction SBRT

Single-fraction SBRT (Stereotactic Body Radiation Therapy) is a precise form of radiation therapy that delivers a high dose of radiation in a single treatment session to a targeted area, often used for treating small, well-defined tumors. This approach minimizes exposure to surrounding healthy tissues while effectively treating the tumor.

RADIATION

multiple-fraction SBRT

Multiple-fraction SBRT (Stereotactic Body Radiation Therapy) is a precise form of radiation therapy that delivers high doses of radiation over several treatment sessions to a targeted area, typically used for treating small, well-defined tumors. This method helps to further protect surrounding healthy tissues by spreading the total radiation dose over multiple sessions.

Trial Locations (15)

3010

RECRUITING

Inselspital - Inselspital, Bern

8901

RECRUITING

UniversitaetsSpital Zurich, Zurich

Unknown

NOT_YET_RECRUITING

Onze Lieve Vrouw Ziekenhuis, Aalst

NOT_YET_RECRUITING

Institut Jules Bordet, Brussels

NOT_YET_RECRUITING

Universitair Ziekenhuis Gent, Ghent

NOT_YET_RECRUITING

AZ Groeninge Kortrijk, Kortrijk

NOT_YET_RECRUITING

Ziekenhuis aan de Stroom (ZAS) - ZAS Augustinus, Wilrijk

NOT_YET_RECRUITING

Azienda Ospedaliero-Universitaria Careggi, Florence

NOT_YET_RECRUITING

Istituto Clinico Humanitas, Milan

NOT_YET_RECRUITING

Istituto Europeo di Oncologia, Milan

NOT_YET_RECRUITING

Sacro Cuore Hospital, Negrar

NOT_YET_RECRUITING

Policlinico Universitario Campus Bio-Medico- Oncology Center, Roma

NOT_YET_RECRUITING

Universita Di Torino, Torino

NOT_YET_RECRUITING

Radiotherapiegroep Arnhem, Deventer

NOT_YET_RECRUITING

Radboudumc - Radboud University Medical Center Nijmegen, Nijmegen

All Listed Sponsors
lead

European Organisation for Research and Treatment of Cancer - EORTC

NETWORK