42
Participants
Start Date
March 25, 2024
Primary Completion Date
May 31, 2024
Study Completion Date
May 31, 2024
Norepinephrine
NE Group (Fluid loading with early norepinephrine administration group) NE Group will receive ringer lactate bolus 20 ml/kg along with norepinephrine infusion at 0.1 mcg/kg/minute until MAP\>5 percentile. Additional fluid boluses of 10-20 ml/kg will be administered (up to a total of 60 ml/kg) until shock resolution or signs of fluid overload are observed, with or without continued norepinephrine infusion according to the treatment group
Ringer's Lactate
Fluid Group will receive ringer lactate bolus 20 ml/ kg only. Additional fluid boluses of 10-20 ml/kg will be administered (up to a total of 60 ml/kg) until shock resolution or signs of fluid overload are observed
Cipto Mangunkusumo Hospital, Jakarta Pusat
Indonesia University
OTHER