Improving Treatment of Major Depressive Disorder by Reducing Negative Future-Oriented Mental Imagery

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

June 1, 2024

Primary Completion Date

October 1, 2025

Study Completion Date

November 1, 2025

Conditions
Major Depressive DisorderMental ImageryCognitive Behavioral Therapy
Interventions
BEHAVIORAL

Future-oriented imagery rescripting

In this pilot study, in the screening phase, negative or catastrophic future-oriented images will be explored for all patients, including ratings of distress. The future-oriented imagery rescripting consists of 3-5 sessions; each image will be treated in one session, starting with the image that causes highest distress. The protocol is largely based on Hackmann (1998), with minor adaptations from other protocols.

OTHER

Treatment as Usual

Psychotherapy and/or medication

Trial Locations (1)

1105 AZ

RECRUITING

Amsterdam UMC (location AMC), Amsterdam

All Listed Sponsors
collaborator

GGZ Eindhoven (participating site)

UNKNOWN

collaborator

Mental Care Group (i.e., HSK group and Mentaal Beter; participating sites)

UNKNOWN

collaborator

Praktijk V (participating site)

UNKNOWN

collaborator

ZonMw (funding)

UNKNOWN

collaborator

Depressie Vereniging (patient association)

UNKNOWN

collaborator

MIND (civil society organization)

UNKNOWN

lead

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER