Assessment of Different Clinical Techniques to Treat Patients With Chronic Low Back Pain

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

July 10, 2024

Primary Completion Date

April 30, 2025

Study Completion Date

May 31, 2025

Conditions
Chronic Low Back Pain (CLBP)
Interventions
DRUG

NSAIDs (Nonsteroidal Anti-Inflammatory Drugs):

"Objective: To reduce pain and inflammation associated with chronic low back pain.~Medications: Ibuprofen, Naproxen, or Diclofenac.~Dosage:~Ibuprofen: 400-600 mg every 6-8 hours as needed. Naproxen: 250-500 mg twice daily as needed. Diclofenac: 50 mg three times daily as needed. Administration: Oral tablets. Duration: Daily use as prescribed, for the duration of the study. Monitoring: Regular follow-up visits to monitor pain levels, side effects, and adherence."

PROCEDURE

Standard Physical Therapy

"Objective: To improve mobility, strength, and reduce pain.~Techniques:~Stretching exercises. Strengthening exercises for core and back muscles. Manual therapy techniques. Postural training. Frequency: Twice a week sessions. Duration: 45-60 minutes per session. Monitoring: Progress will be assessed during each session and adjusted as necessary"

PROCEDURE

Neuromodulation via Dorsal Root Ganglion (DRG):

"Objective: To modulate excitatory pathways and reduce pain through targeted stimulation.~Procedure:~Placement of electrodes near the DRG. Application of pulsed radiofrequency (RF) at 42°C for 3-20 minutes.~Frequency:~Initial treatment: Once a week for the first month. Maintenance: Monthly sessions if needed. Duration: Each session lasts approximately 30-45 minutes. Monitoring: Pain levels and functional improvement will be assessed before and after each session."

PROCEDURE

Platelet-Rich-Plasma Therapy

"Objective: To promote healing and reduce inflammation through the application of concentrated platelets.~Procedure:~Blood draw from the patient. Centrifugation to separate platelets. Injection of PRP into the affected area of the lower back.~Frequency:~Initial treatment: Once a week for the first three weeks. Follow-up: Additional injections may be given based on patient response and clinical judgment.~Duration: Each session lasts approximately 30-45 minutes. Monitoring: Pain levels, inflammation markers, and functional improvement will be assessed before and after each injection."

Trial Locations (1)

Unknown

RECRUITING

Iffat Anwar Medical Complex, Lahore

All Listed Sponsors
lead

Iffat Anwar Medical Complex

OTHER