NCT06448286View on ClinicalTrials.gov

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

December 1, 2025

Primary Completion Date

June 1, 2028

Study Completion Date

June 1, 2029

Conditions
Glioblastoma
Interventions
PROCEDURE

Chemical Exchange Saturation Transfer Magnetic Resonance Imaging

Undergo CEST MRI

PROCEDURE

Contrast-enhanced Magnetic Resonance Imaging

Undergo contrast-enhanced MRI

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

RADIATION

Radiation Therapy

Undergo standard of care radiation therapy

PROCEDURE

Surgical Procedure

Undergo surgical resection

DRUG

Temozolomide

Given PO

Trial Locations (1)

90095

UCLA / Jonsson Comprehensive Cancer Center, Los Angeles

All Listed Sponsors
lead

Jonsson Comprehensive Cancer Center

OTHER