Intrinsic Respiratory Rate Assessment During Mechanical Ventilation to Accelerate Spontaneous Breathing and Extubation

NANot yet recruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

July 30, 2024

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2027

Conditions
Reverse TriggeringPatient Ventilator Dyssynchrony
Interventions
OTHER

brief test

"The intervention is a simple brief test as follows: With the ventilator set with the patient clinical settings, it will be performed an up to 30sec-long or two inspiratory effort and-expiratory occlusion maneuver on the ventilator and/or switch the patient to pressure support for up to 30sec-long to assess the presence of intrinsic respiratory rate.~If an intrinsic respiratory rate ≥8 breaths per minute is present and P/F ratio is ≥150 it will be performed a 5-minute test in pressure support ventilation with the pressure support level to match the clinical setting of the patient. If the patient tolerates well 5 minutes in pressure support (see criteria below) the clinical team will be informed:~\- It will be indicated that the patient tolerated 5 min of PSV and suggest to the clinicians and physician in charge to transition the patient to pressure support ventilation plus suggest reducing sedation."

All Listed Sponsors
lead

Unity Health Toronto

OTHER

NCT06445049 - Intrinsic Respiratory Rate Assessment During Mechanical Ventilation to Accelerate Spontaneous Breathing and Extubation | Biotech Hunter | Biotech Hunter