Therapy-Associated Saliva and Taste Change Evaluation (TASTE) in Head & Neck Cancer Patients Undergoing Radiotherapy

RecruitingOBSERVATIONAL
Enrollment

150

Participants

Timeline

Start Date

December 19, 2022

Primary Completion Date

October 31, 2025

Study Completion Date

December 31, 2027

Conditions
Head and Neck Cancer
Interventions
DIAGNOSTIC_TEST

Repetitive (semi-)objective and subjective taste, smell, and saliva analysis

"Study participants will undergo repetitive assessments of their taste, smell and saliva, using quality of life questionnaires, taste strips, sniffin sticks, and analysis of salivary function and composition.~Assessments will be done before treatment, in the 4th week (+/- 1 week) and last week of radiation therapy (+/- 1 week), and at 6 months (+/- 1 months) and 1 and 2 years post-therapy (+/- 3 months).~At the minimum, participants are expected to complete the assessments at baseline and 1 year after the end of radiation therapy. Assessments at all other time points are strongly encouraged but will be optional."

Trial Locations (3)

3010

NOT_YET_RECRUITING

Universitätsspital Bern, Bern

5001

RECRUITING

Kantonsspital Aarau, Zentrum für Radio-Onkologie KSA-KSB, Aarau

8091

NOT_YET_RECRUITING

Universitätsspital Zürich, Zurich

All Listed Sponsors
collaborator

Kantonsspital Aarau

OTHER

collaborator

University of Bern

OTHER

collaborator

University of Zurich

OTHER

lead

Sonja Stieb, MD

OTHER