Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer

A treatment cycle of 4 weeks, with 5 mg orally once daily for 3 weeks, followed by a 1-week break

2.8 g/m² (400mg bolus + 2.4g/m² continuous infusion) given every 2 weeks through hepatic arterial infusion

85 mg/m² given every 2 weeks through hepatic arterial infusion