First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy

PHASE1RecruitingINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

September 25, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2027

Conditions
Non Small Cell Lung Cancer
Interventions
DRUG

[89Zr]Zr-DFO-emapalumab

Radiotracer \[89Zr\]Zr-DFO-emapalumab administration followed by 3 PET Scans (day 0, day 1 and day 3-5) within 14 days of starting immunotherapy and repeated once 25-45 days after immunotherapy started

Trial Locations (1)

48201

RECRUITING

Karmanos Cancer Institute, Detroit

All Listed Sponsors
lead

Nerissa T. Viola

OTHER