Antibacterial Effect and Substantivity of a New Chlorhexidine and Cymenol Gel on Oral Biofilm and Saliva

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

June 30, 2023

Study Completion Date

July 31, 2023

Conditions
HealthySalivaBiofilms
Interventions
DRUG

0.20% CHX gel on saliva

In vivo application of a gel on the vestibular and palatal/lingual gingival mucosa of both arches at minute 0 for posterior saliva collection at different time-points.

DRUG

0.20% CHX and Cymenol gel on saliva

In vivo application of a gel on the vestibular and palatal/lingual gingival mucosa of both arches at minute 0 for posterior saliva collection at different time-points.

DRUG

0.20% CHX gel on oral biofilm

Ex vivo application of a gel on the glass disks of the removable intraoral appliance at minute 0 for subsequent one-by-one disk removal from the device at different time-points.

DRUG

0.20% CHX and Cymenol gel on oral biofilm

Ex vivo application of a gel on the glass disks of the removable intraoral appliance at minute 0 for subsequent one-by-one disk removal from the device at different time-points.

Trial Locations (1)

15782

University of Santiago de Compostela, Santiago de Compostela

All Listed Sponsors
collaborator

Lacer, S.A.

UNKNOWN

lead

University of Santiago de Compostela

OTHER