NCT06433284View on ClinicalTrials.gov

Comparative Study of Decellularized Human Amniotic Membrane Hydrogel and Inverted Internal Limiting Membrane Flap in Idiopathic Large Macular Holes

NANot yet recruitingINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

January 30, 2027

Study Completion Date

January 30, 2027

Conditions
Macular Holes
Interventions
PROCEDURE

25-gauge pars plana vitrectomy with inverted flap technique and SF6 tamponade

"Standard 3 port 25-gauge pars plana vitrectomy with inverted flap technique after brilliant blue dye staining and SF6 tamponade. Flower petal type of inverted flap will be performed - multiple small ILM flaps will be created around the macular hole and placed over the macular hole"

PROCEDURE

25-gauge pars plana vitrectomy with complete internal limiting membrane peeling with amniotic membrane hydrogel filling and SF6 tamponade

Standard 3 port 25-gauge pars plana vitrectomy with complete internal limiting membrane peeling around the macular hole after brilliant blue dye staining then filling the hole with amniotic membrane hydrogel and sulfur hexafluoride (SF6) tamponade

All Listed Sponsors
lead

Walailak University

OTHER

NCT06433284 - Comparative Study of Decellularized Human Amniotic Membrane Hydrogel and Inverted Internal Limiting Membrane Flap in Idiopathic Large Macular Holes | Biotech Hunter | Biotech Hunter