Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS

NANot yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
FatigueWalking, DifficultyMultiple Sclerosis
Interventions
DEVICE

Transcutaneous Electrical Nerve Stimulation

Transcutaneous electrical nerve stimulation (TENS) is a safe, relatively cheap, and non-painful stimulation of the peripheral sensory and motor nerves. The stimulator is easy to operate and pwMS can apply the stimulation themselves at home. This makes TENS an interesting tool to augment sensory input. A high frequency and long pulse duration is used.

BEHAVIORAL

Movement

Participants are instructed to perform plantar- and dorsi-flexion contraction in a relatively slow tempo. The movement of the ankle is measured by an MRI-compatible potentiometer and participants receive feedback of this movement on the screen inside the scanner.

All Listed Sponsors
lead

University Medical Center Groningen

OTHER

NCT06432686 - Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS | Biotech Hunter | Biotech Hunter